Bacterial infections: Why antibiotics don’t always work against C. diff

  • Experts say most Clostridioides difficile (C. diff) infections occur while taking antibiotics.
  • Researchers say antibiotics aren’t always effective in these cases because the medications can reduce the amount of “good” bacteria in the gut and can sometimes cause the bacteria to become more drug-resistant.
  • A second, longer treatment regimen of antibiotics is sometimes prescribed.
  • Experts say there are foods you can eat and liquids you can drink that can also help.

By Eileen Bailey on May 11, 2023

Fact checked by Jill Seladi-Schulman, Ph.D.

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